Bacterial Protein Toxins

by ; ; ;
Format: Hardcover
Pub. Date: 2003-01-01
Publisher(s): Amer Society for Microbiology
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Summary

U.S. Food and Drug Administration, Bethesda, MD. Text gives an historical overview of bacterial toxins. Also presents a summary of the current knowledge of bacterial toxins with regard to bioterrorism, the spread of antibiotic resistance, and the emergence of new bacterial pathogens. For practitioners. DNLM: Bacterial Toxins.

Table of Contents

Contributors vii
Foreword xi
R. John Collier
Preface xv
I. GENETICS AND REGULATION 1(66)
Two-Component Systems
3(22)
Scott Stibitz
Regulation of Bacterial Toxin Synthesis by Iron
25(14)
Shelley M. Payne
AraC Family Regulators and Transcriptional Control of Bacterial Virulence Determinants
39(16)
Dara W. Frank
Meredith L. Hunt
Quorum Sensing
55(12)
Everett C. Pesci
Barbara H. Iglewski
II. TOXIN BIOGENESIS: CROSSING BACTERIAL MEMBRANE BARRIERS 67(62)
Type V Export Systems: Proteins That Export Themselves
Drusilla L. Burns
The Type I Export Mechanism
71(10)
Vassilis Koronakis
Jeyanthy Eswaran
Colin Hughes
Toxins and Type II Secretion Systems
81(14)
Maria E. Scott
Maria Sandkvist
Type III Secretion Systems
95(20)
Gregory V. Plano
Kurt Schesser
Matthew L. Nilles
Pathogenicity Islands
Jorg Hacker
Type IV Secretion Systems
115(14)
Drusilla L. Burns
III. TOXIN DELIVERY INTO EUKARYOTIC CELLS 129(58)
Receptors for Bacterial Toxins
131(18)
Catharine B. Saelinger
Domain Structures of Bacterial Toxins
Stephen H. Leppla
Recombinant Immunotoxins
David J. FitzGerald
Robert J. Kreitman
Ira Pastan
Direct Penetration of Bacterial Toxins across the Plasman Membrane
149(8)
Franca R. Zaretzky
Mary C. Gray
Erik L. Hewlett
Transport of Toxins across Intracellular Membranes
157(16)
Kirsten Sandvig
Transcytosis of Bacterial Toxins across Mucosal Barriers
173(14)
Bonny L. Dickinson
Wayne I. Lencer
Lipid Rafts
Bonny L. Dickinson
Wayne I. Lencer
IV. TOXIN ACTION 187(122)
Membrane-Damaging Toxins: Pore Formation
189(14)
F. Gisou van der Goot
The Vacuolating Toxin VacA of Helicobacter pylori
F. Gisou van der Goot
Membrane-Damaging Toxins: Family of RTX Toxins
203(12)
Camilla Oxhamre
Agneta Richter-Dahlfors
Bacterial Toxins that Covalently Modify Eukaryotic Proteins by ADP-Ribosylation
215(14)
Joseph T. Barbieri
Drusilla L. Burns
Discovery that the Active Sites of Pseudomonas aeruginosa Exotoxin A and the Heat-Labile Enterotoxin of Escherichia coli Are Superimposable
Wim Hol
Glucosylating and Deamidating Bacterial Protein Toxins
229(16)
Klaus Aktories
Plant and Bacterial Toxins as RNA N-Glycosidases
245(12)
Angela Melton-Celsa
Alison D. O'Brien
Cytolethal Distending Toxin
257(14)
Lawrence A. Dreyfus
Proteases
271(12)
Ornella Rossetto
Fiorella Tonello
Cesare Montecucco
Landmarks in Tetanus and Botulinum Research
Ornella Rossetto
Fiorella Tonello
Cesare Montecucco
Bacterial Toxins that Modulate Rho GTPase Activity
283(10)
James B. Bliska
Gloria I. Viboud
Staphylococcal and Streptococcal Superantigens
293(16)
Patrick M. Schlievert
V. BACTERIAL TOXINS: FRIENDS AND FOES 309(2)
Toxins as Vaccines and Adjuvants
311(16)
Mariagrazia Pizza
Vega Masignani
Rino Rappuoli
Nefarious Uses of Bacterial Toxins
327
Drusilla L. Burns
Joseph T. Barbieri
Color Plates 256(79)
Index 335

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