Basic Immunology : The Functions and Disorders of the Immune System

by ;
Edition: 2nd
Format: Paperback
Pub. Date: 2004-01-01
Publisher(s): Elsevier Science Health Science div
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Summary

The 2nd edition of this popular text emphasizes the fundamental concepts and principles of human immunology that students need to know, without overwhelming them with extraneous material. It leads the reader to a firm understanding of basic principles, using full-color illustrations; short, easy-to-read chapters; color tables that summarize key information clinical cases; and much more-all in a conveniently sized volume that's easy to carry. The New Edition has been thoroughly updated to reflect the many advances that are expanding our understanding of the field. Presents all of the most important principles that govern the function of the immune system. Extrapolates key concepts from the vast amount of experimental data that has emerged. Focuses on cellular interactions in immune responses rather than describing in detail many of the underlying biochemical and molecular mechanisms. Emphasizes immune responses in human rather than experimental animals, drawing upon parallels with experimental situations only when necessary. Uses clear, crisp illustrations, diagrams, figures, charts and tables to highlight important principles. Illustrates how the principles of immunology may be applied to common human diseases through clinical cases in the Appendix. Features an easy-to-read layout; summarizes chapter content in bulleted lists accompanied by review questions; and offers a list of selected readings. all of the scientific advances that are expanding the knowledge base in this rapidly evolving field.

Author Biography

Abul K. Abbas, MBBS: Professor and Chair University of California, San Francisco, School of Medicine Andrew H. Lichtman, MD, PhD: Harvard Medical School; Brigham and Women's Hospital, Boston, Massachusetts

Table of Contents

Introduction to the Immune System: The Nomenclature, General Properties, and Components of the Immune Systemp. 1
Innate Immunity: The Early Defense Against Infectionsp. 21
Antigen Capture and Presentation to Lymphocytes: What Lymphocytes Seep. 41
Antigen Recognition in the Adaptive Immune System: Structure of Lymphocyte Antigen Receptors and the Development of Immune Repertoiresp. 63
Cell-Mediated Immune Responses: Activation of T Lymphocytes by Cell-Associated Microbesp. 83
Effector Mechanisms of Cell-Mediated Immunity: Eradication of Intracellular Microbesp. 105
Humoral Immune Responses: Activation of B Lymphocytes and Production of Antibodiesp. 123
Effector Mechanisms of Humoral Immunity: The Elimination of Extracellular Microbes and Toxinsp. 143
Immunologic Tolerance and Autoimmunity: Self-Nonself Discrimination in the Immune System and Its Failurep. 161
Immune Responses Against Tumors and Transplants: Immunity to Noninfectious Transformed and Foreign Cellsp. 177
Hypersensitivity Diseases: Disorders Caused by Immune Responsesp. 193
Congenital and Acquired Immunodeficiencies: Diseases Caused by Defective Immune Responsesp. 209
Suggested Readingsp. 225
Principal Features of CD Moleculesp. 229
Glossaryp. 263
Clinical Casesp. 291
Indexp. 301
Table of Contents provided by Rittenhouse. All Rights Reserved.

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