Chiral Amine Synthesis Methods, Developments and Applications
by Nugent, Thomas C.Edition: 1st
Format: Hardcover
Pub. Date: 2010-04-05
Publisher(s): Wiley-VCH
Other versions by this Author
-
This Item Qualifies for Free Shipping!*
*Excludes marketplace orders.
List Price: $272.10
Buy New
Arriving Soon. Will ship when available.
$259.14
Rent Textbook
Select for Price
Used Textbook
We're Sorry
Sold Out
eTextbook
We're Sorry
Not Available
Summary
This first comprehensive presentation of this hot and important topic compiles the most up-to-date methods for chiral amine synthesis. The international list of authors reads like a "Who's Who" of the subject, providing a large array of highly practical information concentrated into the useful and essential methods. Following an introductory chapter devoted to helping readers quickly determine which strategies to choose for their investigation, this handbook and ready reference focuses on the examination of methods that are reliable and simultaneously efficient for the synthesis of structurally diverse aliphatic and aromatic chiral amines. Modern methods and applications found in (pharmaceutical) industry are also covered.
Author Biography
Tom Nugent gained his Ph.D. in Organic Chemistry in 1995 from Virginia Tech working with Professor Tomas Hudlicky. From 1996-1997, he completed his postdoctoral studies at the University of Liverpool (Great Britain) with Professor Stanley Roberts.
Over the next six years he worked as a process research chemist, first with Catalytica Fine Chemicals / DSM (Mountain View, California, 1998-2000) and then with Pharmacia/Pfizer Corporation (South San Francisco, California, 2001-2003). In 2004 he began his academic career at Jacobs University as Assistant Professor of Organic Chemistry.
Over the next six years he worked as a process research chemist, first with Catalytica Fine Chemicals / DSM (Mountain View, California, 1998-2000) and then with Pharmacia/Pfizer Corporation (South San Francisco, California, 2001-2003). In 2004 he began his academic career at Jacobs University as Assistant Professor of Organic Chemistry.
Table of Contents
| Stereoselective Synthesis of a-Branched Amines by Nucleophilic Addition of Unstabilized Carbanions to Imines | |
| Asymmetric Methods for Radical Addition to Imino Compounds | |
| Enantioselective Synthesis of Amines by Chiral Brønsted Acid Catalysts | |
| Reduction of Imines with Trichlorosilane Catalyzed by Chiral Lewis Bases | |
| Catalytic, Enantioselective, Vinylogous Mannich Reactions | |
| Chiral Amines from Transition Metal-Mediated Hydrogenation and Transfer Hydrogenation | |
| Asymmetric Reductive Amination | |
| Enantioselective Hydrogenation of Enamines with Monodentate Phosphorus Ligands | |
| Bidentate Ligands for Enantioselective Enamide Reduction | |
| Enantioselective Reduction of Nitrogen-Based Heteroaromatic Compounds | |
| Asymmetric Hydroamination | |
| Enantioselective C&H Amination | |
| Chiral Amines Derived from Asymmetric Aza-Morita-Baylis-Hillman Reaction | |
| Biocatalytic Routes to Nonracemic Chiral Amines | |
| Table of Contents provided by Publisher. All Rights Reserved. |
An electronic version of this book is available through VitalSource.
This book is viewable on PC, Mac, iPhone, iPad, iPod Touch, and most smartphones.
By purchasing, you will be able to view this book online, as well as download it, for the chosen number of days.
Digital License
You are licensing a digital product for a set duration. Durations are set forth in the product description, with "Lifetime" typically meaning five (5) years of online access and permanent download to a supported device. All licenses are non-transferable.
More details can be found here.
A downloadable version of this book is available through the eCampus Reader or compatible Adobe readers.
Applications are available on iOS, Android, PC, Mac, and Windows Mobile platforms.
Please view the compatibility matrix prior to purchase.