Clinical Drug Therapy,9780397553723

Clinical Drug Therapy

by ;
Edition: 5th
ISBN13: 9780397553723
ISBN10: 0397553722
Format: Paperback
Pub. Date: 1998-01-01
Publisher(s): Lippincott Williams & Wilkins
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Table of Contents

Section I INTRODUCTION TO DRUG THERAPY 1(50)
Introduction to Pharmacology
3(8)
Sources of Drugs
4(1)
Drug Nomenclature
4(1)
Sources of Drug Information
4(1)
Federal Drug Laws and Standards
5(1)
Cellular Physiology
6(1)
Cellular Injury and Response to Injury
7(4)
Basic Concepts and Processes
11(11)
Mechanisms of Drug Movement
12(1)
Pharmacokinetics
12(2)
Pharmacodynamics
14(2)
Variables That Affect Drug Actions
16(4)
Adverse Effects of Drugs
20(1)
Tolerance and Cross-Tolerance
21(1)
Administering Medications
22(14)
Preventing Medication Errors
23(1)
Medication Systems
24(1)
Medication Orders
24(1)
Drug Preparations and Dosage Forms
24(1)
Calculating Drug Dosages
25(2)
Routes of Administration
27(9)
Nursing Process in Drug Therapy
36(15)
Using the Prototype Approach to Study Pharmacology
37(1)
Legal Responsibilities of the Nurse
38(1)
Applying the Nursing Process in Drug Therapy
38(3)
Integrating Nursing Process, Drug Therapy, and Clinical Pathways
41(1)
General Principles of Drug Therapy
41(10)
Section II DRUGS AFFECTING THE CENTRAL NERVOUS SYSTEM 51(156)
Physiology of the Central Nervous System
53(8)
Characteristics and Functions of the CNS
54(6)
Drugs Affecting the CNS
60(1)
Narcotic Analgesics and Narcotic Antagonists
61(17)
Pain
62(1)
Endogenous Analgesia System
63(1)
Narcotic Analgesics
63(1)
Classifications and Individual Drugs
63(4)
Agonists/Antagonists
67(3)
Principles of Therapy
70(8)
Analgesic-Antipyretic-Anti-inflammatory and Related Drugs
78(16)
Description
79(1)
Prostaglandins
79(1)
Mechanism of Action
80(1)
Indications for Use
80(1)
Contraindications for Use
80(1)
Individual Drugs
81(6)
Principles of Therapy
87(7)
Antianxiety and Sedative-Hypnotic Drugs
94(16)
Anxiety
95(1)
Sleep and Insomnia
95(1)
Drugs Used to Treat Anxiety and Insomnia
95(4)
Mechanisms of Action
99(1)
Indications for Use
100(1)
Contraindications for Use
100(2)
Principles of Therapy: Benzodiazepines
102(8)
Antipsychotic Drugs
110(16)
Psychosis
111(1)
Schizophrenia
111(1)
Antipsychotic Drugs
112(1)
Individual Antipsychotic Drugs
113(6)
Principles of Therapy
119(7)
Antidepressants
126(15)
Depression
127(1)
Antidepressant Drugs
128(3)
Individual Antidepressants
131(2)
Principles of Therapy
133(8)
Anticonvulsants
141(13)
Seizure Disorders
142(1)
Anticonvulsant Drugs
142(1)
Individual Anticonvulsant Drugs
143(4)
Principles of Therapy
147(7)
Antiparkinson Drugs
154(9)
Parkinson's Disease
155(1)
Antiparkinson Drugs
155(1)
Individual Antiparkinson Drugs
156(2)
Principles of Therapy
158(5)
Skeletal Muscle Relaxants
163(6)
Skeletal Muscle Relaxants
164(2)
Principles of Therapy
166(3)
Anesthetics
169(15)
General Anesthesia
170(1)
Regional Anesthesia
170(1)
Adjuncts to Anesthesia
171(1)
Individual Anesthetic Agents
172(5)
Principles of Therapy
177(7)
Alcohol and Other Drug Abuse
184(16)
Abuse and Dependence
185(1)
CNS Depressants
186(6)
CNS Stimulants
192(2)
Marijuana
194(1)
Hallucinogens
195(1)
Volatile Solvents (Inhalants)
196(1)
Principles of Therapy
197(3)
Central Nervous System Stimulants
200(7)
Uses
201(1)
Types of Stimulants
201(1)
Indications for Use
201(1)
Contraindications for Use
201(1)
Individual CNS Stimulants
201(2)
Principles of Therapy
203(4)
Section III DRUGS AFFECTING THE AUTONOMIC NERVOUS SYSTEM 207(52)
Physiology of the Autonomic Nervous System
209(5)
The Autonomic Nervous System
210(3)
Characteristics of Autonomic Drugs
213(1)
Adrenergic Drugs
214(12)
Description
215(1)
Individual Adrenergic Drugs
216(4)
Principles of Therapy
220(6)
Antiadrenergic Drugs
226(14)
Description
227(2)
Individual Antiadrenergic Drugs
229(4)
Principles of Therapy
233(7)
Cholinergic Drugs
240(8)
Description
240(1)
Individual Cholinergic Drugs
240(4)
Principles of Therapy
244(4)
Anticholinergic Drugs
248(11)
Description
249(2)
Individual Anticholinergic Drugs
251(2)
Principles of Therapy
253(6)
Section IV DRUGS AFFECTING THE ENDOCRINE SYSTEM 259(114)
Physiology of the Endocrine System
261(5)
The Endocrine System
262(1)
Endocrine System-Nervous System Interactions
262(1)
General Characteristics of Hormones
262(3)
General Characteristics of Hormonal Drugs
265(1)
Hypothalamic and Pituitary Hormones
266(9)
Description
267(1)
Therapeutic Limitations
268(1)
Individual Hormonal Agents
268(3)
Principles of Therapy
271(4)
Cortiocosteroids
275(20)
Endogenous Corticosteroids
276(2)
Exogenous Corticosteroids (Glucocorticoids)
278(8)
Principles of Therapy
286(9)
Thyroid and Antithyroid Drugs
295(13)
Description and Uses
296(1)
Thyroid Disorders
296(3)
Individual Drugs
299(3)
Principles of Therapy
302(6)
Hormones That Regulate Calcium and Phosphorus Metabolism
308(14)
Description
309(2)
Hypocalcemia
311(2)
Principles of Therapy: Drugs Used in Hypocalcemia
313(2)
Hypercalcemia
315(3)
Principles of Therapy: Drugs Used in Hypercalcemia
318(4)
Antidiabetic Drugs
322(29)
Endogenous Insulin
323(2)
Diabetes Mellitus
325(3)
Hypoglycemic Drugs
328(8)
Principles of Therapy
336(15)
Estrogens, Progestins, and Oral, Contraceptives
351(14)
Estrogens
352(1)
Progesterone
353(1)
Estrogens and Progestins Used as Drugs
353(1)
Individual Estrogens, Progestins, and Oral Contraceptives
354(5)
Principles of Therapy
359(6)
Androgens and Anabolic Steroids
365(8)
Androgens
366(1)
Anabolic Steroids
366(1)
Testosterone
366(1)
Abuse of Androgenic and Anabolic Steroid Drugs
367(1)
Characteristics of Androgenic and Anabolic Steroid Drugs
367(3)
Principles of Therapy
370(3)
Section V NUTRIENTS, FLUIDS, AND ELECTROLYTES 373(60)
Nutritional Products, Anorexiants, and Digestants
375(17)
Nutritional Products
376(1)
Anorexiants
376(1)
Individual Nutrititional Products for Oral or Tube Feeding
376(6)
Intravenous Fluids
382(1)
Pancreatic Enzymes
383(1)
Principles of Therapy
384(8)
Vitamins
392(16)
Description and Uses
393(10)
Principles of Therapy
403(5)
Minerals and Electrolytes
408(25)
Description and Uses
409(2)
Individual Agents Used in Mineral-Electrolyte and Acid-Base Imbalances
411(12)
Principles of Therapy
423(10)
Section VI DRUGS USED TO TREAT INFECTIONS 433(122)
General Characteristics of Antimicrobial Drugs
435(19)
Microorganisms and Infections
436(5)
Host Defense Mechanisms
441(2)
Characteristics of Anti-infective Drugs
443(3)
Principles of Therapy
446(8)
Beta-Lactam Antibacterials: Penicillins, Cephalosporins, and Others
454(18)
Description
455(1)
Mechanisms of Action
455(1)
Penicillins
455(8)
Cephalosporins
463(1)
Carbapenems
464(1)
Monobactam
464(1)
Principles of Therapy: Beta-Lactam Antibacterials
465(7)
Aminoglycosides and Fluoroquinolones
472(11)
Aminoglycosides
473(3)
Fluoroquinolones
476(1)
Principles of Therapy: Aminoglycosides and Fluoroquinolones
477(6)
Tetracyclines, Sulfonamides and Urinary Agents
483(12)
Tetracyclines
484(5)
Sulfonamides
489(1)
Urinary Drugs
490(1)
Principles of Therapy: Tetracyclines
491(1)
Principles of Therapy: Sulfonamides and Urinary Antiseptics
491(4)
Macrolides and Miscellaneous Antibacterials
495(11)
Macrolides
496(1)
Miscellaneous Antibacterial Drugs
497(3)
Principles of Therapy: Macrolides and Miscellaneous Antibacterials
500(6)
Drugs for Tuberculosis and Mycobacterium Avium Complex (MAC) Disease
506(12)
Tuberculosis
507(1)
Prevention and Treatment of Tuberculosis
507(1)
Characteristics of Antitubercular Drugs
508(1)
Individual Antitubercular Drugs
509(2)
Mycobacterium avium Complex (MAC) Disease
511(1)
Principles of Therapy
512(6)
Antiviral Drugs
518(16)
General Characteristics of Viruses and Viral Infections
519(1)
Antiviral Drugs
519(8)
Principles of Therapy
527(7)
Antifungal Drugs
534(8)
Fungi and Fungal Infections
535(1)
Antifungal Drugs
535(3)
Principles of Therapy
538(4)
Antiparasitics
542(13)
Protozoal Infections
543(1)
Helminthiasis
544(1)
Scabies and Pediculosis
545(1)
Individual Antiparasitic Drugs
545(6)
Principles of Therapy
551(4)
Section VII DRUGS AFFECTING THE IMMUNE SYSTEM 555(58)
Physiology of the Immune System
557(10)
Overview of Body Defence Mechanisms
558(1)
Immunity
558(1)
Immune Cells
559(5)
Patient-Related Factors That Influence Immune Function
564(1)
Immune Disorders
565(1)
Immunotherapy
566(1)
Immunizing Agents
567(18)
Immunization
568(1)
Agents for Active Immunity
568(1)
Agents for Passive Immunity
568(1)
Individual Immunizing Agents
568(12)
Principles of Therapy
580(5)
Immunostimulants
585(11)
Description
586(4)
Individual Immunostimulants
590(1)
Principles of Therapy
591(5)
Immunosuppressants
596(17)
Description
597(1)
Autoimmune Disorders
597(1)
Tissue and Organ Transplantation
597(3)
Corticosteroids
600(1)
Cytotoxic Agents
600(4)
Principles of Therapy
604(9)
Section VIII DRUGS AFFECTING THE RESPIRATORY SYSTEM 613(36)
Physiology of the Respiratory System
615(3)
The Respiratory System
616(1)
Disorders of the Respiratory System
617(1)
Drug Therapy
617(1)
Bronchodilating and Antiasthmatic Drugs
618(13)
Respiratory Disorders
619(1)
Drug Therapy
619(1)
Individual Bronchodilating and Antiasthmatic Drugs
620(5)
Principles of Therapy
625(6)
Antihistamines
631(9)
Histamine and Its Receptors
632(1)
Antihistamines
632(4)
Principles of Therapy
636(4)
Nasal Decongestants, Antitussives, Mucolytics, and Cold Remedies
640(9)
Description
641(1)
Individual Drugs
642(2)
Principles of Therapy
644(5)
Section IX DRUGS AFFECTING THE CARDIOVASCULAR SYSTEM 649(110)
Physiology of the Cardiovascular System
651(4)
Heart
652(1)
Blood Vessels
652(1)
Blood
653(1)
Drug Therapy in Cardiovascular Disorders
653(2)
Cardiotonic-Inotropic Agents Used in Congestive Heart Failure
655(12)
Congestive Heart Failure
656(1)
Digitalis Preparations
656(4)
Principles of Therapy
660(7)
Antiarrhythmic Drugs
667(17)
Description
668(1)
Cardiac Eletrophysiology
668(1)
Cardiac Arrhythmias
668(3)
Antiarrhythmic Drugs
671(1)
Classifications and Individual Drugs
671(8)
Principles of Therapy
679(5)
Antianginal Drugs
684(11)
Angina Pectoris
685(1)
Antianginal Drugs
685(2)
Individual Antianginal Drugs
687(3)
Principles of Therapy
690(5)
Drugs Used in Hypotension and Shock
695(7)
Hypotension and Shock
696(1)
Antishock Drugs
696(1)
Individual Drugs Used in Hypotension and Shock
696(2)
Principles of Therapy
698(4)
Antihypertensive Drugs
702(19)
Regulation of Arterial Blood Pressure
703(1)
Hypertension
703(1)
Antihypertensive Drugs
704(2)
Individual Drugs
706(7)
Principles of Therapy
713(8)
Diuretics
721(13)
Description
722(1)
Renal Physiology
722(3)
Alterations in Renal Function
725(1)
Diuretic Drugs
725(3)
Principles of Therapy
728(6)
Anticoagulant, Antiplatelet, and Thrombolytic Agents
734(14)
Description
735(1)
Blood Coagulation
735(1)
Thrombotic and Thromboembolic Disorders
735(1)
Drugs Used in Thrombotic and Thromboembolic Disorders
736(1)
Individual Drugs
737(4)
Principles of Therapy
741(7)
Antilipemics and Peripheral Vasodilators
748(11)
Antilipemic Drugs and Peripheral Vasodilators
749(1)
Atherosclerosis
749(1)
Blood Lipids
749(2)
Hyperlipidemia
751(1)
Drugs Used to Treat Hyperlipidemia
751(3)
Principles of Therapy
754(5)
Section X DRUGS AFFECTING THE DIGESTIVE SYSTEM 759(50)
Physiology of the Digestive System
761(4)
The Digestive System
762(1)
Organs of the Digestive System
762(1)
Secretions of the Digestive System
762(2)
Effects of Drugs on the Digestive System
764(1)
Drugs Used in Peptic Ulcer Disease
765(15)
Peptic Ulcer Disease
766(1)
Types of Antiulcer Drugs
766(8)
Principles of Therapy
774(6)
Laxatives and Cathartics
780(9)
Description
781(1)
Defecation
781(1)
Laxatives and Cathartics
781(4)
Principles of Therapy
785(4)
Antidiarrheals
789(11)
Description
790(6)
Principles of Therapy
796(4)
Antiemetics
800(9)
Nausea and Vomiting
801(1)
Antiemetic Drugs
801(4)
Principles of Therapy
805(4)
Section XI DRUGS USED IN SPECIAL CONDITIONS 809(78)
Antineoplastic Drugs
811(24)
Characteristics of Normal Cells
812(1)
Characteristics of Malignant Neoplasms
812(4)
Characteristics of Antineoplastic Drugs
816(2)
Individual Drugs
818(5)
Drugs That Reduce Toxicity of Antineoplastic Drugs
823(4)
Principles of Therapy
827(8)
Drugs Used in Ophthalmic Conditions
835(16)
Structures of the Eye
836(1)
Disorders of the Eye
836(1)
Ophthalmic Drugs
837(1)
Individual Drugs
838(7)
Principles of Therapy
845(6)
Drugs Used in Dermatologic Conditions
851(17)
Functions of the Skin
852(1)
Disorders of the Skin
852(2)
Types of Dermatologic Drugs
854(1)
Individual Drugs
855(8)
Principles of Therapy
863(5)
Drug Use During Pregnancy and Lactation
868(19)
Pregnancy and Lactation
869(1)
Maternal-Placental-Fetal Circulation
869(1)
Drug Effects on the Fetus
870(1)
Fetal Therapeutics
870(1)
Maternal Therapeutics
870(7)
Abortifacients
877(1)
Tocolytics
878(1)
Drugs Used During Labor and Delivery at Term
879(1)
Neonatal Therapeutics
879(1)
Principles of Therapy
880(7)
Appendix A: Miscellaneous Drugs 887(2)
Appendix B: The International System of Units 889(1)
Appendix C: Therapeutic Serum Drug Concentrations for Selected Drugs 890(1)
Appendix D: Canadian Drug Laws and Standards 891(1)
Appendix E: Canadian Drug Names 892(8)
Index 900

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