This book will serve as a very useful resource for physicians dealing with, and interested in, this very complex and evolving branch of neurology.The book will provide an introduction to basic neuroimmunology and principles of immunotherapy. It will also serve as a comprehensive guide to immune-mediated disorders of the central and peripheral nervous system and other systemic disorders with a significant neuroimmunologic component. Special emphasis will be given to multiple sclerosis and related disorders. The chapters will be written by experts in their fields and will include the most up to date scientific information. The book will target neurologists, residents and fellows, internists, and general practitioners who treat patients with neurologic disorders and other systemic autoimmune diseases. An attempt will be made to simplify complex immunological mechanisms and to focus on practical patient related issues.