Fluorinated Heterocyclic Compounds Synthesis, Chemistry, and Applications
by Petrov, Viacheslav A.Edition: 1st
Format: Hardcover
Pub. Date: 2009-09-28
Publisher(s): Wiley
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Summary
Fluorinated compounds have distinctive desirable properties suitable for use in pharmaceuticals and agrichemicals, especially their ability to penetrate the cell membrane barrier for drug absorption. This essential reference provides the latest state-of-the-art information on key application areas within fluorine chemistry. With contributions from experts from both industry and academia, the book covers the chemistry, synthesis and applications of fluorinated heterocycles with chapters on three-, four-, five-, six- and seven-membered fluorine-containing heterocycles, fluorinated nucleosides, and fluorointermediates and fluoropolymers.
Author Biography
Viacheslav A. Petrov is a Research Fellow with DuPont Central Research and Development in Wilmington, Delaware.
Table of Contents
| Preface | p. vii |
| Contributors | p. xi |
| Introduction: Nomenclature of Polyfluorinated Heterocycles | p. xiii |
| Synthesis and Chemistry of Fluorinated Heterocycles | p. 1 |
| Fluorinated Three-Membered Ring Heterocycles | p. 3 |
| Fluorinated Four-Membered Heterocycles | p. 65 |
| Fluorinated Five-Membered Nitrogen-Containing Heterocycles | p. 91 |
| Fluorinated Five-Membered Heterocycles Containing Oxygen, Sulfur, Selenium, and Phosphorus | p. 159 |
| Synthesis of Fluorinated Sugars from Fluorine-Containing Synthons | p. 227 |
| Synthesis of Ring-Fluorinated Pyridines | p. 243 |
| Synthesis and Chemical Transformation of Six-Membered Aromatic Heterocycles Containing Perfluoroalkyl Groups | p. 273 |
| Perfluorinated Six-Membered Aromatic Heterocycles Containing One or More Heteroatom | p. 303 |
| Perfluorinated Nonaromatic Heterocycles | p. 325 |
| Seven-Membered and Larger Ring-Fluorinated Heterocycles | p. 361 |
| Application of Fluorinated Heterocyclic Materials | p. 397 |
| Agricultural Products Based on Fluorinated Heterocyclic Compounds | p. 399 |
| Pharmaceuticals Containing Fluorinated Heterocyclic Compounds | p. 419 |
| Practical Uses of Fluorinated Heterocycles | p. 493 |
| Index | p. 507 |
| Table of Contents provided by Ingram. All Rights Reserved. |
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