From Multi-scale Modeling to Meso-science - A Chemical Engineering Perspective presents the results of three decades of research into the energy-minimization multi-scale (EMMS) model for multi-phase systems in chemical engineering, including its philosophy, principles, modeling, computation and applications. The EMMS principle is that compromise exists in the competition between dominant mechanisms. This book shows the universality of the EMMS principle for all meso-scale phenomena existing between elementary particles and the universe with respect to both physics and mathematics, and discusses a unifying, emerging science - which is called meso-science. The ability of the EMMS paradigm to help achieve multi-scale computation is also demonstrated. The book concludes with perspectives on meso-science and virtual process engineering. The work is interdisciplinary in nature, and is applicable not only to chemical engineering, from where it originated, but also to other fields where meso-scale phenomena exist. It can be used as a textbook, reference for research, and for an industrial development guide. Jinghai Li is Vice-President of the Chinese Academy of Sciences (CAS), a professor at the Institute of Process Engineering, CAS, and is a group leader of the EMMS Group.Wei Ge, Wei Wang and Ning Yang are professors at the EMMS Group, part of the CAS's Institute of Process Engineering.Xinhua Liu, Limin Wang, Xianfeng He and Xiaowei Wang are associate professors at the EMMS Group, part of the CAS's Institute of Process Engineering.Junwu Wang is a professor at the EMMS Group, part of the CAS's Institute of Process Engineering.Mooson Kwauk is an emeritus director of the CAS's Institute of Process Engineering and is an advisor to the EMMS Group.