Master Control Genes in Development and Evolution
by Gehring, Walter J.Format: Hardcover
Pub. Date: 1998-12-01
Publisher(s): Yale Univ Pr
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Summary
In this book, one of the world's most eminent developmental biologists discusses some of the exciting new insights into how genes control development. Walter Gehring describes in vivid detail his essential contributions to the landmark discovery of the homeobox, a characteristic DNA segment found in the genes of all higher organisms from the fruitfly to humans, and he explains how this has provided the key to our modern understanding of development and evolution. The book thus becomes not only a lucid discussion of genetics but also an engaging description of the art of scientific investigation.
Author Biography
Walter J. Gehring is professor in the department of cell biology at the University of Basel, Switzerland.
Table of Contents
| Foreword | |
| Preface | |
| Chronology | |
| The Ancient Language of Genes | p. 1 |
| The Key to Understanding Development: Homeotic Genes | p. 21 |
| Gene Cloning and the Discovery of the Homeobox | p. 39 |
| How to Generate an Embryo? | p. 55 |
| The Secret is in the Egg | p. 93 |
| From Gradients to Stripes | p. 107 |
| The Master Control Genes | p. 123 |
| The Molecular Basis | p. 137 |
| Enhancer Trapping and Hunting for Target Genes | p. 153 |
| The Wiring of the Nervous System | p. 163 |
| Metamorphosis and Transdetermination | p. 171 |
| The Role of Homeotic Genes in Evolution | p. 181 |
| A Deep Look into the Eyes | p. 197 |
| Theories About Fertilization | p. 211 |
| Sperm and Inheritance | p. 212 |
| Drosophilia Life Cycle | p. 213 |
| Glossary | p. 215 |
| Further Reading | p. 221 |
| Index | p. 227 |
| Table of Contents provided by Blackwell. All Rights Reserved. |
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