NMS Immunology,9780683306620

NMS Immunology

by
Edition: 4th
ISBN13: 9780683306620
ISBN10: 0683306626
Format: Paperback
Pub. Date: 2000-08-25
Publisher(s): LWW
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Summary

This is a concise, outlined review of basic and clinical immunology. The USMLE format questions make it an excellent resource for exam preparation. It also helps students practice problem solving and critical thinking in immunology.

Table of Contents

Preface vii
Acknowledgments ix
To the Reader xi
Introduction to Immunity and the Nonspecific Immune System
1(18)
Immunity
1(2)
Mechanical, chemical, and physiologic factors
3(1)
Phagocytosis
4(6)
Humoral factors
10(2)
Lymphocytic cells
12(7)
Immunogens and Immunizations
19(14)
Immunogenicity
19(2)
Immunogens
21(1)
Adjuvants
22(1)
Immunization
22(1)
Active immunization
23(2)
Passive immunization
25(2)
Experimental immunization procedures
27(6)
Immunoglobulins
33(20)
Immunoglobulins
33(1)
General immunoglobulin structure
33(5)
Structure and function of specific immunoglobulins
38(3)
Antibody diversity
41(6)
Plasma cell dyscrasias
47(6)
The Complement System
53(18)
Complement
53(2)
Pathways of complement activation
55(5)
The membrane attack pathway (the common pathway)
60(1)
Biologic consequences of complement activation
61(3)
Regulatory mechanisms
64(7)
The Immune Response System and Its Regulation
71(28)
Hematopoiesis
71(1)
Macrophages
72(1)
The lymphoid system
73(3)
General characteristics of T cells
76(7)
General characteristics of B cells
83(1)
Exposure to an antigenic substance
84(3)
Phases of the humoral immune response
87(1)
Regulation of the immune response
88(1)
Immunosuppression
89(2)
Tolerance
91(1)
Immunopotentiation
92(7)
Laboratory Methods
99(10)
In vitro antigen-antibody reactions
99(1)
Procedures involving direct demonstration and observation of reactions
99(3)
Complex serologic procedures
102(2)
Assays of immune competence
104(1)
Identification of immediate (type I) hypersensitivity reactions due to lgE
105(1)
Production and use of monoclonal antibodies
106(3)
Immunologic Mechanisms of Tissue Damage
109(20)
Introduction
109(1)
Immediate hypersensitivity (type I) reactions
109(5)
Cytotoxic (type II) reactions
114(2)
Immune complex-mediated (type III) reactions
116(3)
Cell-mediated reactions (type IV): delayed hypersensitivity and cell-mediated cytotoxicity
119(10)
Autoimmune Diseases
129(20)
General considerations
129(5)
Representative autoimmune diseases
134(15)
Immunodeficiency Disorders
149(18)
General considerations
150(1)
Phagocytic cell defects
151(2)
B-cell deficiency disorders
153(2)
T-cell deficiency disorders
155(1)
Combined B-cell and T-cell deficiency disorders
156(2)
Secondary immunodeficiency conditions
158(1)
Complement deficiencies
159(8)
Transplantation and Tumor Immunology
167(28)
Transplantation
167(13)
Tumor immunology
180(15)
Case Studies 195(20)
Comprehensive Examination 215(38)
Appendix---Normal Values 253(2)
Index 255

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