Organofluorine Chemistry Synthesis, Modeling, and Applications

By presenting novel methods for the efficient preparation of fluorinated compounds and their application in pharmaceutical and agrochemical chemistry as well as medicine, this is a valuable source of information for all researchers in academia and industry!

K�lm�n J. Szab� is professor at the Department of Organic Chemistry at the Arrhenius Laboratory, Stockholm University (Sweden), since 2003. His major research interests are method development in organic synthesis, catalytic reactions, organoboron and organofluorine (including fluorine-18) chemistry. He is a member of the Royal Swedish Academy of Sciences and has authored over 150 publications. He is the editor of the book "Pincer and Pincer-Type Complexes" (Wiley-VCH).

Nicklas Selander is an assistant professor at the Department of Organic Chemistry at Stockholm University (Sweden), since 2018. His research interests include organic synthesis methodology, catalysis, and radical chemistry.

Preface
1. Catalytic Synthesis of Organofluorine Species Including Fluorine-18 Labelled Compounds
2. Trifluoromethylation and Fluoroalkylation with Hypervalent Iodines
3. Selective Fluorination Methods Including Fluor-18 Labelling
4. Asymmetric Fluorination Reactions
5. Fluorine in Pharmaceutical Industry
6. Fluorine in the Design of Active Ingredients for Modern Crop Protection
7. Radical Fluorination and Trifluoromethylation
8. Bifunctionalization Based Catalytic Fluorination and Trifluoromethylation
9. Fluorination, Trifluoromethylation and Trifluoromethylthiolation of Alkenes, Cyclopropanes and Diazo Compounds
10. Development of Fluoration and Fluoroalkylation Reagents
11. Introduction of SCF3 Group into Organic Molecules
12. Fluorination and Fluoroalkylation of Aromatic and Heteroaromatic Molecules
13. Trifluoromethylation Based Bifunctionalization Reaction
14. Photoredox Catalysis in Fluorination and Trifluoromethylation Reactions
15. Selective Difluorination with Ar-IF2 Reagent, Properties of Vicinally Difluorinated Compounds
16. Stereoselective Catalytic Introduction of F/CF3/SCF3 Functional Groups
17. DFT Modelling of Catalytic Fluorination Reactions.
18. Integrated DFT Modelling and Experimental Approach to Catalytic Synthesis of Organofluorines
19. Chemistry of OCF3, SCF3 and SeCF3 Functional Groups
20. Selective Trifluoromethylation and Fluoroalkylation of Unsaturated Compounds