Practical Transfusion Medicine, 2nd Edition
by Editor: Michael F. Murphy (Worldwide Clinical Trials, Atlanta, Georgia, and London, UK); Editor: Derwood H. Pamphilon (Institute of Transfusion Sciences and Royal Hospital for Sick Children, Bristol); Foreword by: David WeatherallEdition: 2nd
Format: Hardcover
Pub. Date: 2005-08-01
Publisher(s): Wiley-Blackwell
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Summary
Essential practical manual for all those working in modern transfusion medicine Why Buy This Book?--Concise and 'user friendly' guide to transfusion medicine-Provides guidance for everyday clinical questions-Revised and updated throughout to reflect rapid developing areas-Scope broadened by including experts from the USAThis comprehensive guide to transfusion medicine has a practical and didactic approach. The text is divided into five main sections. The first deals with the basic principles of transfusion, and includes the background science of the blood group system and immunity. The second section deals with the use of transfusion in the range of clinical settings and this is followed by a section on the complications of transfusion and their management. The fourth section covers the organisational issues related to transfusion practice from donors and blood collection to medico-legal aspects. The final section takes a look at the future developments in the field and the implications for transfusion practice.This book is ideal for trainee haematologists revising for exams and as a reference book by clinical haematology staff faced with specific problems.
Author Biography
Michael F. Murphy, Consultant Haematologist, Deptartment of Haematology, The John Radcliffe Hospital, Oxford, UK
Derwood H. Pamphilon, Consultant Haematologist, Institute for Transfusion Sciences, Bristol, UK
Table of Contents
| List of Contributors | p. vii |
| Foreword | p. xi |
| Preface to the second edition | p. xiii |
| Preface to the first edition | p. xv |
| Basic principles of transfusion | |
| Introduction | p. 3 |
| Essential immunology for transfusion medicine | p. 13 |
| Human blood group systems | p. 24 |
| Human leucocyte antigens | p. 34 |
| Platelet and neutrophil antigens | p. 50 |
| Clinical transfusion practice | |
| The effective and safe use of blood components | p. 67 |
| Bleeding associated with trauma and surgery | p. 86 |
| Prenatal and childhood transfusions | p. 97 |
| Haematological disease | p. 119 |
| Transfusion strategies in organ transplant patients | p. 132 |
| Inherited and acquired coagulation disorders | p. 138 |
| Uses of intravenous immunoglobulin | p. 151 |
| Complications of transfusion | |
| Haemolytic transfusion reactions | p. 161 |
| Febrile reactions and transfusion-related acute lung injury | p. 171 |
| Urticarial and anaphylactic reactions | p. 179 |
| Bacterial contamination | p. 184 |
| Post-transfusion purpura | p. 191 |
| Immunomodulation and graft-versus host disease | p. 195 |
| Transfusion-transmitted infections | p. 208 |
| Variant Creutzfeldt-Jakob disease | p. 229 |
| Practice in blood centres and hospitals | |
| Donors and blood collection | p. 241 |
| Blood donation testing and the safety of the blood supply | p. 250 |
| Production and storage of blood components | p. 259 |
| Medicolegal aspects | p. 274 |
| Blood transfusion in hospitals | p. 280 |
| Autologous transfusion | p. 298 |
| Tissue banking | p. 309 |
| Cord blood banking | p. 320 |
| Therapeutic apheresis | p. 328 |
| Developments in transfusion medicine | |
| Blood substitutes | p. 341 |
| Cytokines in transfusion practice | p. 350 |
| Haemopoietic stem cell processing and storage | p. 357 |
| Haemopoietic stem cell transplantation and immunotherapy | p. 369 |
| Gene therapy | p. 390 |
| Recombinant antibodies and other proteins | p. 403 |
| Blood transfusion in a global context | p. 415 |
| The design of interventional trials in transfusion medicine | p. 424 |
| Getting the most out of the evidence for transfusion medicine | p. 436 |
| The future of transfusion medicine | p. 445 |
| Index | p. 457 |
| Table of Contents provided by Ingram. All Rights Reserved. |
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