Remote C-H Bond Functionalizations Methods and Strategies in Organic Synthesis

Presenting a systematic compilation of distal C-H functionalizations which belongs to the most important topics in present day organic synthesis. Essential for every synthetic chemist.

Debabrata Maiti received his PhD from John Hopkins University (USA) in 2008 under the supervision of Prof. Kenneth D. Karlin. After postdoctoral studies at the Massachusetts Institute of Technology (MIT) with Prof. Stephen L. Buchwald (2008 - 2010), he joined the Department of Chemistry at IIT Bombay in 2011, where he is currently an Associate Professor. He is also a Visiting Faculty at University of Pavia, Italy. Professor Maiti has authored about 114 scientific publications and has received numerous scientific awards. He is also the Associate Editor of the Journal of Organic Chemistry and member of Editorial Advisory Board of Organometallics and Chemistry - An Asian Journal.

Srimanta Guin graduated from Sree Gopal Banerjee College, Burdwan University in 2007 and obtained his M.Sc degree from Visva-Bharati University in 2009. He received his doctoral degree in organic synthesis from Indian Institute of Technology Guwahati under the supervision of Prof. Bhisma Kumar Patel in 2015. He then joined Prof. Debabrata Maiti as a National Post-doctoral Fellow in 2016. His current research interest is focused on the development of transition metal catalyzed distal C-H functionalization of arenes and aliphatic substrates.

Introduction
Transition Metal Catalyzed (Pd, Rh, Cu) Meta C-H Functionalization of Arenes by Directing Group Approach
Norbornene Mediated Distal C-H Functionalization of Haloarenes
Directing Group Assisted Meta C-H Functionalization by Catellani Reaction
Ruthenium Catalyzed Remote C-H Functionalization
Carboxylic Group as a Traceless Directing Group for Distal C(sp2)-H Functionalization
Harnessing Non-Covalent Interaction for Distal C(sp2)-H Functionalization by Ir and Pd
Non-Directed Distal C(sp2)-H Functionalization
Transition Metal Catalyzed Para C-H Functionalization of Arenes
Functionalization of Indoles and Related Heterocycles at Distal Positions (other than C2 and C3)
Mechanistic Perspective for Distal C(sp2)-H Activation
Directing Group Assisted Distal C(sp3)-H Functionalization of Acid, Amine, Ketone, Alcohol, and Thiol.
Radically Initiated Distal C(sp3)-H Functionalization
The Enzymatic Distal C(sp2)-H and C(sp3)-H Activation