Vander's Renal Physiology, 7th Edition
by Eaton, Douglas; Pooler, JohnEdition: 7th
Format: Paperback
Pub. Date: 2009-03-30
Publisher(s): McGraw-Hill Medical
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Summary
The structure, function, and pathologies of the human kidney - simplified and explained ..Written in a concise, conversational style this trusted text reviews the fundamental principles of renal physiology that are essential for an understanding of clinical medicine. Combining the latest research with a fully integrated teaching approach,Vander's Renal Physiology ...Features: . Offers the best review of renal physiology available for the USMLE Step 1. Begins with the basics and works up to advanced principles. Distills the essence of renal processes and their regulation in a concise, integrated manner that focuses on the logic of renal processes. Features learning aids such as flow charts, diagrams, key concepts, clinical examples, learning objectives, and review questions with answers and explanations. Explains the relationship between blood pressure and renal function. Presents the normal functions of the kidney with clinical correlations to disease states. Includes the most current research on the molecular and genetic principles underlying renal physiology .
Author Biography
Douglas C. Eaton, PhD is a Professor of Physiology and Pediatrics at Emory University in the School of Medicine, Atlanta, Georgia.
.John P. Pooler, PhD is an Associate Professor of Physiology at Emory University in the School of Medicine, Atlanta, Georgia.
Table of Contents
| Preface | p. vii |
| Renal Functions, Anatomy, and Basic Processes | p. 1 |
| Functions | p. 2 |
| Anatomy of the Kidneys and Urinary System | p. 4 |
| The Nephron | p. 5 |
| Blood Supply to the Nephrons | p. 12 |
| Basic Renal Processes | p. 16 |
| Renal Blood Flow and Glomerular Filtration | p. 24 |
| Glomerular Filtration and Renal Blood Flow | p. 25 |
| Flow, Resistance, and Pressure in the Kidneys | p. 25 |
| Glomerular Filtration | p. 26 |
| Autoregulation | p. 34 |
| Clearance | p. 38 |
| Clearance Units | p. 39 |
| Plasma Creatinine and Urea Concentrations as Indicators of GFR Changes | p. 43 |
| Basic Transport Mechanisms | p. 47 |
| Crossing the Epithelial Barriers | p. 47 |
| Receptor-Mediated Endocytosis and Transcytosis | p. 53 |
| Transport Mechanisms in Reabsorption | p. 55 |
| Renal Handling of Organic Substances | p. 63 |
| Active Proximal Reabsorption of Organic Nutrients (eg, Glucose, Amino Acids) | p. 64 |
| Proteins and Peptides | p. 66 |
| Active Proximal Secretion of Organic Anions | p. 68 |
| Active Proximal Secretion of Organic Cations | p. 70 |
| pH Dependence of Passive Reabsorption or Secretion | p. 74 |
| Urea | p. 74 |
| Basic Renal Processes for Sodium, Chloride, and Water | p. 77 |
| Overview | p. 78 |
| Individual Tubular Segments | p. 84 |
| Urinary Concentration: The Medullary Osmotic Gradient | p. 93 |
| Control of Sodium and Water Excretion: Regulation of Plasma Volume and Plasma Osmolality and Renal Control of Systemic Blood Pressure | p. 102 |
| Regulation of Blood Pressure | p. 104 |
| Contribution of the Kidney to the Regulation of Sodium Excretion and Blood Pressure | p. 110 |
| Control of Water Excretion | p. 131 |
| Renal Regulation of Potassium Balance | p. 140 |
| Regulation of Potassium Between the Intracellular and Extracellular Compartments | p. 141 |
| Renal Potassium Handling | p. 143 |
| Regulation of Hydrogen Ion Balance | p. 155 |
| Guidelines for Studying Acid-Base Biology | p. 156 |
| Renal Handling of Acids and Bases | p. 162 |
| Renal Excretion of Acid and Base | p. 165 |
| Hydrogen Ion Excretion on Urinary Buffers | p. 167 |
| Phosphate and Organic Acids as Buffers | p. 169 |
| Hydrogen Ion Excretion on Ammonium | p. 170 |
| Quantification of Renal Acid-Base Excretion | p. 174 |
| Regulation of the Renal Handling of Acids and Bases | p. 176 |
| Control of Renal Glutamine Metabolism and NH4+ Excretion | p. 177 |
| Intravenous Solutions: Lactated Ringer's | p. 178 |
| Specific Categories of Acid-Base Disorders | p. 179 |
| Renal Response to Metabolic Acidosis and Alkalosis | p. 180 |
| Factors Causing the Kidneys to Generate or Maintain A Metabolic Alkalosis | p. 181 |
| Regulation of Calcium and Phosphate Balance | p. 185 |
| Effector Sites for Calcium Balance | p. 188 |
| Hormonal Control of Effector Sites | p. 192 |
| PTH | p. 193 |
| Overview of Renal Phosphate Handling | p. 197 |
| Answers to Study Questions | p. 201 |
| p. 209 | |
| p. 211 | |
| Index | p. 213 |
| Table of Contents provided by Ingram. All Rights Reserved. |
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